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atovaquone and proguanil HCI
Today I took my first ever dosage of a malaria prophylaxis, which happens to be called MALARONE (or otherwise: atovaquone and proguanil HCI). Tomorrow I am traveling to Mozambique for two weeks for work and I’m hoping this keeps me safe from the Anopheles mosquito.
East Africa is considered a malaria-endemic area. For Mozambique the malaria risk is predominantly due to Plasmodium falciparum and exists throughout the year in the whole country. P. falciparum, the most deadly of the four types of malaria, is resistant to chloroquine and sulfadoxine-pyrimethamine, which are two different types of anti-malarial medications. I’ll see how Malarone does.
The following is more info on malaria from the Travel Doctor website:
Malaria is a serious and sometimes fatal disease which is widespread in many tropical and subtropical countries. It is caught by being bitten by an infected mosquito that is carrying the malaria parasites in its saliva.
The malaria parasite is a microscopic organism called a Plasmodium and it belongs to the group of tiny organisms known as protozoans. There are four types of plasmodium: P. falciparum (the most dangerous), P. vivax, P. ovale and P. malariae. The species of mosquito that carries the malaria parasites is the Anopheles mosquito.
These parasites enter the host’s bloodstream when bitten by an infected mosquito and then migrate to the liver where they multiply before returning back into the bloodstream to invade the red blood cells. The parasites continue to multiply inside the red cells until they burst releasing large numbers of free parasites into the blood plasma causing the characteristic fever associated with the disease. This phase of the disease occurs in cycles of approximately 48 hours.
The free parasites are then able to infect any mosquito that feeds on the host’s blood during this phase. The cycle then continues as the parasites multiply inside the mosquito and eventually invade its salivary glands. (see the plasmodium life cycle below).
Malaria occurs in over 100 countries and more than 40% of the people in the world are at risk. Large areas of Central and South America, Hispaniola (Haiti and the Dominican Republic), Africa, the Middle East, the Indian subcontinent, Southeast Asia, and Oceania are considered malaria-risk areas.

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As most of you have probably heard and/or read by now, a massive earthquake hit coastal Peru south of Lima on Wednesday, 15 August. Currently the death toll is over 500 and thousands have been displaced. 